The former head of the Institute of Science - Professor Molnar, returns to the Institute to seek treatment for his heart condition. The new director of the Institute, and his former assistant, Dr. Egberg had a falling out with Molnar after the latter considered his research unethical. However, after waking up from surgery, Molnar makes a horrifying discovery; Egberg has swapped their brains!

A bioterrorism incident occurs at a university in Western Australia. Chris and Piers from BSAA's anti-bioterrorism unit head to the scene to investigate, and they cooperate with former S.T.A.R.S. member Rebecca, who is teaching at the university. On the scene, they meet a mysterious young man named Tyler Howard…

Thirteen men and women wake up in a mansion, not knowing who each other is or why they have been abducted. To escape from the mansion, infested by Zombies, they must work together but cannot set aside their suspicions that one or more of their number is involved.

Triton Indutries has created a genetically-engineered creature using DNA from human sources. During the course of the experiment, however, the host mother carrying the mutant escapes from the laboratory compound, giving birth shortly thereafter. The intellient "baby" beings hunting down and killing its male DNA donors, while at the same time trying to mate with its female donors. The head of the lab wants to destroy the monster before the press can get wind of the story, but the former head of security wants to expose the whole thing.

在汤姆和杰克死后，贝基和吉尔继续在僵尸末日中前行。她们的目标仅仅是生存下去，直到她们看到了指向一个避难所的神秘标志。

特赖登生化公司在进行着一种利用人体DNA基因改造生物的特殊试验，但在实验过程中一名受孕女性突然逃跑使得基因生物流失。为了追回试验品，公司主管丹尼医生不惜一切代价甚至牺牲他人生命，与此同时两个绿色环保组织的记者也在对他们进行紧追不舍的追踪中……

Alien monster uses a psychic to try to take over the earth.

《生化危机4：孵化》收录于Capcom在2006年发售的游戏同捆DVD中。影片将《生化危机4》（原版）里昂和艾达两条路线整合，按照时间顺序重新剪辑，完整展现了游戏的剧情。战斗部分大量采用了官方才能做出的摄影机视角画面，尤其是BOSS战场景颇有新意，对玩家而言值得一看。

暂无剧情简介

The story concerns a new biohazard crisis in the small town of Rosa Enferma, Mexico. This time around, multiple parties, new and old, are involved. As the S.T.A.R.S. members investigate the new bioagent (and battling the undead), old memories resurface, including a nightmare “returning to his fleshly body, resurrected and whole.”