The four best friends are confident, smart, having fun, discussing men, relationships and sex. But they're also taking care of kids, or they just had kids, or they're pregnant. Sara has a nice ass, so she started taking pictures of it and living in the world of social media. Hedvika lives in a bit of a golden cage, her workaholic husband isn't home much, so it's no wonder she's charmed by the young busker David. Zuzana, after her break-up with Kamil, is penniless, just a worked-up and hurried mother of two. Slovak immigrant Eliska, on the other hand, has a great boyfriend, unbearable parents, is pregnant and is sick of everything.

Two women and a child seek refuge in an ATM vestibule when pursued by an angry man who wants money — money they don't have.

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Aldona is the single mother of a daughter, Miglė, who is soon to become a mother herself.​When Miglė comes to visit for the weekend during the last days of her pregnancy, Aldona tries to show how much she cares, but instead starts to control her daughter. Step by step, Aldona pushes the boundaries between the two, until she crosses the line.

In Cambodia, a sudden law criminalizes surrogacy, and 32 women are arrested, forced to raise the children they gave birth to for others. In Italy, a bill that makes surrogacy a universal crime threatens the intended parents who have relied on it. And Lia, the daughter of two fathers born through that practice, asserts her right to exist. Mothers weaves together three stories that reveal how control over women’s bodies becomes the ground on which everyone’s freedom is contested.

Based on the novel by Teodora Dimova, the series shows the lives of six families and the relationships between children and parents.

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The story of two women, one French and the other German, who fight for a child who has been mistakenly taken by the Germans after a bomb raid.

Adele Dayton, a famous actress, visits her daughter, Mildred, whom she left with relatives as an infant. Her guardians, Mazie and John, permit the visit provided Adele conceals her relationship from Mildred. While Adele is there, she unintentionally attracts the admiration of Mildred's sweetheart, aspiring playwright David Starke, when she helps him sell one of his plays to a Broadway producer. David goes to New York city to open the play, neglecting Mildred. On opening night Mildred visits Adele and finds her in an embrace with David; she upbraids Adele for stealing David's affection from her and returns to her home in Massachusetts. Realizing she has hurt her own daughter, Adele sacrifices her love for David, snubbing him with a cold shoulder, he soon returns to Mildred and they marry.

Mitsu Tamura (Kyoka Suzuki) is the mother of 7 sons. Her sons are sent to the battlefield and 6 of her sons die on the battlefield. To mend her broken heart, she talks to 7 paulownia trees which she planted whenever one of her sons left for the battlefield.