The series shows life through the eyes of a little girl named Ningning. Born in a secluded island called Isla Baybay, Ningning grew up living a simple life with her father Dondon, her mother Lovely, and her grandmother Mamay. As a fisherman, Dondon barely earns enough to make ends meet but the constant support and love of his family makes him feel like the richest man in the world. Through their love for each other, everyday in Ningning's life seems happy and content. As fate would have it, a strong typhoon ravished the island and destroyed the boat by which Dondon makes his living. This forced the family to leave for the city to find a better life. Although faced with many challenges in their life in the city, Ningning and her family showed that though hope, perseverance, love of family and friends, all things are achievable. Through the eyes of Ningning the world takes on an innocent perception full of beautiful relationships, second chances, forgiveness, and love.

Bituing Walang Ningning is a Filipino television serial drama. It began airing on ABS-CBN on May 15, 2006, and ended on October 6 that year. For most of its run, the soap opera was the network's highest rating show in primetime. The station referred to the TV series as SineSerye, meaning Movie Serialized TV Series.The series was supposed to end on September 25, 2006 but ended on September 6 due to coverage of the Special concert staged at the Araneta Colesseum and a taped interview for the series on the 19th and also rehearsals tapings and dubbings which were occurring during the run. The finale was in 5 parts for its finale week and also introduced its current Primetime Series and Pilot Maging Sino Ka Man on the 6th with its Pilot moved to a different timeslot and would also be the replacement of the Phenominal Series. On October 8, 2006 a "Himig of Pasasalamat Concert" was staged at the Araneta with all of the characters which was also televised live the series also showed a glimpse of behind the scenes footage and also sung the themes from its successful Album produced by Star Records and Viva Records although it was said that some parts of the series was supposed to also be produced by Viva such as songs sung by Sarah Geronimo herself and the theme of the song originally popularized by Cuneta in the film.