Morgan submits Sabrina's article to a contest and she lands a job at Scorch magazine. Zelda and Hilda move back to the Other Realm and Sabrina and friends move into their house.

Sabrina Spellman, a perfectly normal 16-year-old, is informed by her aunts, Hilda and Zelda, that she (and they, and her whole family on her father's side) are witches. She lives with them in Massachusetts while preparing to receive her witch's license. Along the way, she gets into many scrapes while figuring out how certain spells work. She also has to keep the secret from her boyfriend, Harvey, friends Jenny and later Valerie, stuck-up nemesis Libby, and her ever-suspicious vice-principal, Mr. Kraft.

It's a day for celebration when Sabrina finally receives notice that she has earned her Witches License. Before the Other Realm ceremony the next day, however, she has a few mortal concerns with which to deal. First, Mr. Kraft has assigned her to pick the theme for the school dance. Second, Harvey and Dashiell are pressuring her to choose between them once and for all. Promised that her license will bring her all the knowledge in the universe, Sabrina puts off her decisions and attends her party in the Other Realm. She is presented with her license, but Hilda and Zelda explain there's a catch. Before she can use it, she must uncover her family secret, and family members will be visiting her periodically to act as her guides. Sabrina is desperate to solve her romantic dilemma, so she turns to her magic book for a spell that will reveal her heart's desire. The next day, Harvey and Dashiell come to school dressed as cowboys and ready for a showdown.

All of Sabrina's responsibilities as student, girlfriend and witch pile up on her as she fails her witch's exam and ends up at witch boot camp.

Sabrina goes to live with her father in Paris.

Sabrina and Miles decide to produce a horror picture and some of the actors may be real monsters.

塞布丽娜（Britt McKillip 配音）出生于女巫世家，家中时代成员都曾进入著名的女巫学校就读，并且以优异的成绩毕业。13岁生日那天，女巫王后出现在了塞布丽娜的面前，送给了她一支魔杖，以及一张女巫学校的录取通知书。就这样，塞布丽娜来到了学校里，在这里展开了全新的生活。 每一个女巫的手心里都会有一颗星星的标记，代表了她们的属性和特质。然而塞布丽娜的标志却只有半颗心，这让塞布丽娜感到了深深的疑惑和自卑。学校里有一个名叫尼克尔（Alexandra Carter 配音）的学生，沉默寡言的她常常受到其他同学的欺凌。塞布丽娜惊奇的发现，尼克尔也只有半颗星星，以此为契机，两个女孩成为了无话不谈的朋友。

小女巫只有 127 岁，对于一年一度的女巫集会来说还太小。虽然她的年龄还不足以成为一名真正的女巫，但她想成为一名真正的好女巫。这个决定给她的魔法世界带来了麻烦。

本影集改编自吉儿·墨菲广受欢迎的书作，描述一名笨笨的女主角在阴差阳错下进入女巫学校就读后，意识到自己可能属于那里。