温以宁和沈聿川离婚后，独自生下儿子温诺，经营一家甜品店努力谋生。一次偶然相遇，沈聿川发现孩子的存在。沈聿川开始学着弥补过往的亏欠，却引来爱慕他的苏曼妮多次恶意刁难。温以宁没有轻易复合，设立相处边界，沈聿川学会尊重女主的事业与选择。历经风波考验，两人解开心结，带着孩子重建完整的家庭。

Ayesha is the elder daughter of rich business tycoon Mr. Verma, an overprotective father who's kept his two daughters away from modern influences. Ayesha goes to college and comes in contact with Ajay, the leader of a group called Aryans, responsible for handling the security at the college. Ajay's soft-spoken nature and humble, down-to-earth attitude soon make Ayesha his most ardent admirer.

故事发生在二战后经济萧条的意大利。贫穷且失去丈夫的莉莉安娜不得不跟儿子尼诺离开故乡博洛尼亚，搬到普利亚和已故丈夫的弟弟佐丹努住在一起。小叔子佐丹努年轻时曾经暗恋过莉莉安娜，她的到来使佐罗努旧情复燃，佐丹努的视线总是追随着漂亮的莉莉安娜，这严重搅乱了他原本平静的生活。佐丹努对莉莉安娜的这种无微不至的关怀引起了两位姑妈桑蒂娜和尤金尼娜强烈的妒恨，她们千方百计想赶母子出门……

剧集讲述了四位年轻妈妈在面对职场压力、生育烦恼以及婚姻琐事时，因为做出了不同选择，而带来不同结果的故事。

《人生第一次》主人公们满怀憧憬准备推开生活之门的状态，《人生第二次》的主人公们经历的正是推开门后，知晓世界百味、直面生活疾风暴雨的决定性阶段。主创团队改变了遵循“人生时钟”的纵向叙事，精选四组对立的关键词展开横向比照，通过“圆”与“缺”、“纳”与“拒”、“是”与“非”、“破”与“立”主题下的八幅人生图景，用多维度多视角观察普通人在面临决定性瞬间时的选择与命运。通过洞察每个独一无二的“人生第二次”故事，展现中国人面对困境的勇气和坚韧，激发观众对生活的勇气，对于人生和未来的多一重思考。

女主姜懿禾因为一场意外与孩子一同死在了手术台上，男主郁宴清在姜懿禾去世后浑浑噩噩，欺骗自己姜懿禾并没有死。六年后郁宴清在公司里遇到与姜懿禾容貌一样的女人萧忆禾，郁宴清想要弥补对姜懿禾的亏欠所以与萧忆禾闪婚，萧忆禾为了哥哥萧池的医药费同意跟郁宴清结婚，后开启了爱恨纠葛。

After moving into a new house with his mom and soon to be father, Lawrence goes through some things. Six months after his mom and new "dad" marry. His mother dies. It isn't easy on Maise's Husband. He soon realizes that he could not deal with Lawrence and goes to a foster home to see if he can put him there. Lawrence has to stay for a few more days before he can leave. Over those days the husband realizes that Lawrence is a great kid.

文森特和路易斯曾经非常相爱，但几个月前他们分手了。一个偶然的机会，文森特获得一个盒子，得以让他重温与路易斯的时光。他会获得第二次机会吗？

After being separated for three years, Laurent (Laurent Delpit) and André (Andre Schneider) meet again for the first time, only to discover that their feelings for one another are everything else but dead. After a long weekend together in Berlin, they decide to give their relationship a second chance.

新婚当夜，秀琴的丈夫不幸离世。婆婆听信迷信，认定秀琴命硬克夫，狠心将她逐出家门。秀琴投奔娘家，家人却打算利用她联姻，不肯接纳。走投无路之际，心地善良的林生心怀恻隐，时常关照接济她，二人慢慢生出深厚情谊。流言接踵而至，婆婆十分恼怒，强行带回秀琴，暗中打算将她改嫁他人。危难之时，林生挺身而出，远赴煤窑辛苦务工筹钱。重重磨难过后，林生成功救下秀琴，两人勇敢冲破世俗偏见，相守相伴，安稳度过余生。