二十岁的唐申申逃离养父母到城里投靠哥哥，不料第一天就丢了包，也丢了联系方式。这一天她遇上了今后十年人生中四个重要的男人：爱人孙六十，友人杜腾飞，恩人温晓健，亲人曾秋锐。非典后准备结婚的孙唐二人因不堪压力分手；唐申申跟随杜腾飞下海售房，准备和温晓健组建家庭，不料对方却在执行公务中负伤残疾；另外万没想到的还有医生曾秋锐就是自己的生父，从不知如何接纳，到重建父女关系，两人最终化解恩怨。温晓健在公司背黑锅遭遇官司，为还他清白，唐申申和检察官陈遥奔走呼告。经过10年沉浮，唐申申最终回到孙六十身边，两人一起寻找幸福。

‘46 years with the second wife of my husband… Life is so ironic.’ The first wife, Mak-i, who lost her two sons to measles and a typhoon, let the second wife, Chun-hee, into the house to carry on a family line. Long after the husband passed away, the two lived together for 46 years, maintaining an ambiguous relationship as if they were mother and daughter, sisters, or friends. A harsh and special bond between two grandmothers. Now they continue to be the most beautiful companions in the world as the only people who will look after each other's end... 　　源自：https://www.eidf.co.kr/eng/movie/view/1357

当父亲的阿兹海默症状越来越严重，吉姆为难于是否继续由自己照顾他。一次危险事件中，父亲差点使得怀孕的妻子发生意外，他不得不做出一个艰难的决定。