内布拉斯加州崖燕的翅膀越来越短，切萨皮克湾的海龟却越来越大。在加拉帕戈斯群岛上，不同的物种正在退化成最开始的模样。为什么会出现这些现象？答案很简单：因为我们。人类已经把这个星球变得面目全非——我们把草原和森林变成了田野和城市，污染了空气和水。这些变化会以非自然选择的方式改变进化的进程。

Having discovered that her dying husband has an illegitimate child living in Florida, a devout Christian housewife leaves her sheltered world on a mission to reunite father and son. 　　When a dutiful, albeit barren Christian housewife discovers that her devout husband has suffered a stroke at a sperm bank where he's been secretly donating his seed for the past 25 years, she leaves her sheltered world and starts off on a journey to find his eldest biological son - a mullet-headed, foul-mouthed ex-con with whom she develops an odd but meaningful relatiоnship.

在“非自然死亡原因研究所”（简称“UDI”）工作的三澄美琴 （ 石原里美 饰）是专门探查死者死因的解剖医生。她最不能容忍的是对“非自然死亡”不闻不问。在她看来，“非自然”的背后必定有着需要法医来追究的真相，比如伪装杀人、医疗失误、未知的疑难疾病等等。然而，在日本，很多非自然死亡的死者都未经解剖就火化了。美琴与她那些个性鲜明的同事们一起，向这样的现实发起了挑战 。