On February 15, 1992 in Milwaukee, Wisconsin, Jeffrey Dahmer, one of the world's most infamous serial killers, was convicted of 15 counts of murder and sentenced to 937 years in federal prison. This movie is based on events from his life.

A secret government lab run by Dr. Hess (Art LaFleur) has been trying to create the ultimate killer using the DNA of infamous killers Jeffrey Dahmer (Ford Austin) and John Wayne Gacy (Randal Malone), but there’s one big problem: they’ve escaped! Bloody mayhem stretches across the United States as they go on the ultimate killing spree. Trying to stop the maniacal madness is Ringo (Ford Austin), a hick warrior being trained by God (Harland Williams), using only a shotgun and a bottle of whiskey. In his road trip to hell, he must first fight off his own demons, not to mention an army of Japanese ninjas and a Super-serial killer (Ethan Phillips)! It all leads up to the ultimate showdown!

This is a fictitious, yet mostly historically accurate account of Jeffrey Dahmer's life as a serial killer, as narrated by Jeffrey Dahmer (Giancarlo Herrera) using many actual quotes. It shows part of his boyhood, and his first murder as a teenager. There are realistic depictions of several of his murders from pick up to dismemberment and eventual consumption, as well as his attempts to create "living zombies" by pouring hydrochloric acid into his victim's skulls. Dahmer's frequent interactions with his friendly neighbor and his grandmother are also shown. In essence, the story explores the psychodynamics of Jeffrey Dahmer's relationships with his victims both pre and postmortem.