A deadly pathogen is unleashed and unknowingly carried to Dana Overbeck's 30th birthday party, where her estranged father, Rufus, is coming to make amends.

The film evokes the era of the 1831 cholera epidemic and the peasant uprising which followed it. The way of Doctor Balás, cholera commissioner, and district administrator Hunyor leads through the mountains of Zemplén and is lined by unburied corpses, peasants dying of the illness and of overdoses of bismuth, by the miserably starving population, the healthy digging mass-graves and by uncultivated lands.