Mathew is a graduate in software engineering, but is now jobless. He is waiting for his good time to get a good job. Mathew has borrowed some money as loan. Now he cannot give it back as he has no job. Mathew's childhood friend Jeena Johnykkutty is ready to help him as she could. She has a job. Her father Johnykkutty does not like Mathew and he always tries to trouble Mathew whenever he gets a chance. At this time Mathew's good time arrives; but along with it many problems too. The gripping events that follow plot the rest of 'Neram'.

Raj, a reporter, is framed for the murder of his wife by the real perpetrator, a powerful billionaire who is a serial rapist and killer. Set on revenge, Raj plots a daring escape from prison and swears he will avenge his wife's death within the next 24 hours.

A woman named Thulsi arrives in the life of a man and makes repeated appearances. It begins to wreck his family life.