本剧改编自耳雅同名小说《S.C.I.谜案集》，讲述了一场正义与邪恶的生死较量的故事，我们一路光明，是因为有人竭力抵挡黑暗。学术究竟是什么？是花哨的幻术，还是杀人于无形的法术，亦或只是哗众取宠的招数？白羽瞳、展耀领衔S.C.I.为你解开环环相扣的谜案。

S.I.S., or Special Investigation Squad, is an elite branch of the LAPD. A new psychopath terrorizing Los Angeles proves to be their hardest case yet.

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Sung-Bum is a hot-tempered detective who relies on his intuition to crack cases. He rarely comes across a case that he cannot solve. The body of a police officer is then discovered in a burned out car near an abandoned building. Drugs are also found near the dead officer. To catch the killer the police department sets up a special investigation unit for the case. Sung-Bum takes part in the investigation. Ho-Ryong is a young, confident man who works as a criminal profiler. He trained with the F.B.I. in the United States. Ho-Ryong is also assigned to the special investigation unit. Ho-Ryong relies on evidence rather than instinct. Detective Sung-Bum takes an immediate dislike for Ho-Ryong.

Three educated but unemployed youths campaign for a politician and help him win an election. When the politician does not give them a job as promised, they hatch a plan to make him toe the line.

Agni, a volatile cop, quits but returns to hunt "Black Tiger," uncovering corruption and vengeance. But a shocking truth threatens to shatter everything he knows.