When Papa Smurf is mysteriously taken by evil wizards, Razamel and Gargamel, Smurfette leads the Smurfs on a mission into the real world to save him. With the help of new friends, the Smurfs must discover what defines their destiny to save the universe.

In this fully animated, all-new take on the Smurfs, a mysterious map sets Smurfette and her friends Brainy, Clumsy and Hefty on an exciting race through the Forbidden Forest leading to the discovery of the biggest secret in Smurf history.