表现1900年八国联军入侵北京，火焚大栅栏，老药铺同仁堂损失惨重。面对着铺面被烧、瘟疫横行、离京避难的大东家病逝归途、老铺即将倒闭的险境，女东家乐…

全剧39个日日夜夜，京味儿、药味儿、火药味儿，惊心动魄；家族、悬疑、情爱，扣人心弦—— 　　1948年(民国37年)12月24日，北平。一派大战前的仓皇景…

1948年12月24日，北平。一派大战前的仓皇景象：电台里不时传出被围的消息，报童在奔走呼号，街头到处是买两块，卖两块的银元倒卖声，军警驱赶着游行队伍，东单机场南逃的飞机像苍蝇一样飞上飞下。 同仁堂在北平立世二百七十余年，如今却面临着歇业的危险。大爷乐柏龄去祁州开市被劫，药料难以为济；三爷乐柏松用轿车换了头驴驮着三奶奶从被围的天津死里逃生，让同仁堂离开古都南迁，掌柜的二爷乐柏年必须做出选择。

A tacky version of the lake sequence in "Zodiac".

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Julio César Chávez reluctantly opens up about his private life and his family. His daughter, Nicole, tries to reunite them through a game, challenging everybody to confront their insecurities. The series features touching and funny moments and depicts a father's struggle to save his children from addiction. A beautiful beachfront celebration highlights a new beginning for the Chávez family