In America it’s an epidemic. Now new evidence raises concern about the UK’s use of prescription opioids. Michael Mosley goes on an immersive journey to ask what can be done about it. 　　The opioid epidemic has devastated America. But what’s the situation here? A new report from Public Health England raises serious concerns about Britain's own relationship with painkillers. Dr Michael Mosley embarks on an immersive journey to Britain’s opioid frontline and meets patients struggling with addiction and GPs fighting a constant battle to help those suffering from chronic pain. He also uncovers worrying evidence of people abusing over-the-counter opioids and discovers how easy it is to buy strong opioids online. 　　Nearly six million people in England and Wales were prescribed an opioid last year. Michael wants to uncover how and why we’re consuming twice the amount of opioids as twenty years ago, especially when the scientific evidence he encounters disturbingly suggests that for the majority of people taking them for chronic pain, these drugs mostly don’t even work. Though a vital tool in our doctors’ armoury to combat acute pain and in cancer and end-of-life care, the Public Health England report revealed that more than half a million people have been on opioids for more than three years. 　　Michael cautions that people taking these drugs should not suddenly stop taking them. Nevertheless, as he discovers, long term or high dose use does leave them exposed to greater risk of side effects including dependency, addiction and even accidental death by overdose. 　　As many as 28 million Britons endure chronic pain - and if we’re to kick what seems like a dangerous national opioid habit, Michael believes that the critical issue is deprescribing. Millions now require help coming off opioids and drug-free alternatives to them. For Michael this is nothing short of a challenge as important as the fight against cancer and heart disease. 　　So how much do people on the ground really know about these powerful painkillers, some of which, including fentanyl, can be many times stronger than heroin? On his travels, Michael meets Karen in Hastings who now believes her five years on increasingly strong opioids ‘turned her into a zombie’. But he also encounters Brenda in Salford who thinks the morphine she has taken for fifteen years to help with her excruciating back pain is the thing that makes her life just about bearable. And he spends time with Vicki whose 50+-a-day over-the-counter painkiller habit led to overdose and near death before she finally admitted her addiction and started detox.

In America it’s an epidemic. Now new evidence raises concern about the UK’s use of prescription opioids. Michael Mosley goes on an immersive journey to ask what can be done about it. 　　The opioid epidemic has devastated America. But what’s the situation here? A new report from Public Health England raises serious concerns about Britain's own relationship with painkillers. Dr Michael Mosley embarks on an immersive journey to Britain’s opioid frontline and meets patients struggling with addiction and GPs fighting a constant battle to help those suffering from chronic pain. He also uncovers worrying evidence of people abusing over-the-counter opioids and discovers how easy it is to buy strong opioids online. 　　Nearly six million people in England and Wales were prescribed an opioid last year. Michael wants to uncover how and why we’re consuming twice the amount of opioids as twenty years ago, especially when the scientific evidence he encounters disturbingly suggests that for the majority of people taking them for chronic pain, these drugs mostly don’t even work. Though a vital tool in our doctors’ armoury to combat acute pain and in cancer and end-of-life care, the Public Health England report revealed that more than half a million people have been on opioids for more than three years. 　　Michael cautions that people taking these drugs should not suddenly stop taking them. Nevertheless, as he discovers, long term or high dose use does leave them exposed to greater risk of side effects including dependency, addiction and even accidental death by overdose. 　　As many as 28 million Britons endure chronic pain - and if we’re to kick what seems like a dangerous national opioid habit, Michael believes that the critical issue is deprescribing. Millions now require help coming off opioids and drug-free alternatives to them. For Michael this is nothing short of a challenge as important as the fight against cancer and heart disease. 　　So how much do people on the ground really know about these powerful painkillers, some of which, including fentanyl, can be many times stronger than heroin? On his travels, Michael meets Karen in Hastings who now believes her five years on increasingly strong opioids ‘turned her into a zombie’. But he also encounters Brenda in Salford who thinks the morphine she has taken for fifteen years to help with her excruciating back pain is the thing that makes her life just about bearable. And he spends time with Vicki whose 50+-a-day over-the-counter painkiller habit led to overdose and near death before she finally admitted her addiction and started detox.

Horizon is BBC Two's flagship 50-minute science documentary series. In September 2004 it celebrated its 40th anniversary and it continues to enjoy outstanding critical acclaim. Recognised as the world leader in its field, it regularly wins a sweep of international science, medical and environmental film accolades, and has recently won the Royal Television Society Award and the Prix Italia. In 2002, the British Academy of Film & Television Arts presented Horizon with the BAFTA Television Award for Best Factual Series or Strand. In 2003 it won the prestigious Images et Science award for best medical documentary and the Carl von Linne Award at the Living Europe film festival in Sweden. That year, a Horizon co-production with WGBH Boston won the Emmy for best documentary.

Horizon is BBC Two's flagship 50-minute science documentary series. In September 2004 it celebrated its 40th anniversary and it continues to enjoy outstanding critical acclaim. Recognised as the world leader in its field, it regularly wins a sweep of international science, medical and environmental film accolades, and has recently won the Royal Television Society Award and the Prix Italia. In 2002, the British Academy of Film & Television Arts presented Horizon with the BAFTA Television Award for Best Factual Series or Strand. In 2003 it won the prestigious Images et Science award for best medical documentary and the Carl von Linne Award at the Living Europe film festival in Sweden. That year, a Horizon co-production with WGBH Boston won the Emmy for best documentary.

在一名男子失去孩子后，他开始了一场消灭类鸦片流行背后的白领罪犯的运动，并不情愿地接受了他的反英雄身份。

本片讲述了用一种神奇的药物来唤醒失去的记忆。

第1集 　　在本集节目中团队提出了一个最基本的问题，猫如何通过看听和嗅，来认识周围的世界。对于人类来说视觉是主要的感官，那么猫呢？ 　　第2集 　　本节目将揭示你所喜爱的宠物，如何转变成好斗的猎食者。我们的猫和它们的大型猫科远亲有着相同的捕猎天性，它们也表现出了巡逻和保护自己领地的需要。但大型猫科动物是野生动物而猫找到了成为宠物的方法，那么它们是如何适应和发展出与人类共处的能力的呢。宠物猫似乎并不怕害我们，一些猫甚至积极地寻求我们的陪伴。 　　第3集 　　世界顶级的猫类科学家将进行一项史无前例的科学研究，来发现我们猫类朋友的秘密生活，向你展示不可思议的猫语，它们会发出颤音，会发出咘咘的有趣叫声。实验将向你展示猫如何让彼此知道它们是朋友亦或敌人，我们睡觉时它们有着不可思议的对话，以及它们为何如此让人喜爱。本期节目将向你揭示猫类的秘密语言以及它们对你的倾诉。

第1集 　　在本集节目中团队提出了一个最基本的问题，猫如何通过看听和嗅，来认识周围的世界。对于人类来说视觉是主要的感官，那么猫呢？ 　　第2集 　　本节目将揭示你所喜爱的宠物，如何转变成好斗的猎食者。我们的猫和它们的大型猫科远亲有着相同的捕猎天性，它们也表现出了巡逻和保护自己领地的需要。但大型猫科动物是野生动物而猫找到了成为宠物的方法，那么它们是如何适应和发展出与人类共处的能力的呢。宠物猫似乎并不怕害我们，一些猫甚至积极地寻求我们的陪伴。 　　第3集 　　世界顶级的猫类科学家将进行一项史无前例的科学研究，来发现我们猫类朋友的秘密生活，向你展示不可思议的猫语，它们会发出颤音，会发出咘咘的有趣叫声。实验将向你展示猫如何让彼此知道它们是朋友亦或敌人，我们睡觉时它们有着不可思议的对话，以及它们为何如此让人喜爱。本期节目将向你揭示猫类的秘密语言以及它们对你的倾诉。

Horizon: The Truth About Looking Young Plastic surgeon Dr Rozina Ali leaves the operating theatre behind for the frontiers of skin science and asks if it is possible to make your skin look younger without surgery. She discovers the latest research about how the foods we eat can protect our skin from damage, and how a chemical found in a squid's eye is at the forefront of a new sun protection cream. She also finds out how sugar in our blood can make us look older, and explores an exciting new science called glycobiology, which promises a breakthrough in making us look younger.

Horizon: The Truth About Looking Young Plastic surgeon Dr Rozina Ali leaves the operating theatre behind for the frontiers of skin science and asks if it is possible to make your skin look younger without surgery. She discovers the latest research about how the foods we eat can protect our skin from damage, and how a chemical found in a squid's eye is at the forefront of a new sun protection cream. She also finds out how sugar in our blood can make us look older, and explores an exciting new science called glycobiology, which promises a breakthrough in making us look younger.