老中医葛仁义和师哥合开一家中医诊所福安堂，师兄的意外辞世，让庸医老葛成了福安堂的一堂之主。老葛的误诊，让福安堂陷入危机，主攻西医的儿媳杜媛媛力挽狂澜，拯救了福安堂。从此福安堂变成了中西合并的诊所。欣喜之余老葛发现，自己在诊所以及家里的霸主地位遭到了动摇，老葛开始与儿媳明争暗斗。老葛扶老太引出一段忘年恋；大儿子葛当归当不了律师当厨师；二儿子葛刀豆要让福安堂上市……故事过后，老葛一家人仍然继续着自己的生活。

老中医边福侠与师哥合开一家医馆福安堂，师兄提出变卖福安堂，出国定居。为了保住福安堂，边家人各出奇招，边福侠成了福安堂的一堂之主。千年媳妇熬成婆…

What can a sexless middle aged married man, whose life now consists mainly of watching Scooby Doo cartoons with a four year old boy, possibly find to write comedy about? Formerly stand-up's youthful iconoclast, Lee now gawps blankly at News 24 as Britain burns down around him, and blinks weirdly at the vast wayside retail outlets during endless journeys to and from increasingly indistinct provincial theatres. 　　Once he lived on the pleasure planet. 　　Now he is trapped in Carpet Remnant World. 　　And so are you.