法兰克福市遭到热浪袭击，市内工人纷纷罢工，堆积如山的垃圾引起鼠患问题，老鼠群在市内无孔不入，更可怕的是它们身上带有一种不知名的可致命病毒。卡田医生急忙研制一种免疫疫苗以拯救市民。但灾难控制员法兰明白到传统的灭鼠方法并不可行，唯一解救方法只有独闯鼠穴……

法兰克福市遭到热浪袭击，市内工人纷纷罢工，堆积如山的垃圾引起鼠患问题，老鼠群在市内无孔不入，更可怕的是它们身上带有一种不知名的可致命病毒。卡田医生急忙研制一种免疫疫苗以拯救市民。但灾难控制员法兰明白到传统的灭鼠方法并不可行，唯一解救方法只有独闯鼠穴……

承接第一部剧情，一群食肉老鼠通过水管道再次来袭，恐怖鼠患围攻家园。

In the 1990s, a South American city is rocked by the imminent outbreak of a plague. While many attempt to flee the city, Dr Bernard Rieux sends his sick wife away and does his best to care for the plague's victims. The plague means different things to different people: to the doctor, it's a disease to be cured. To a pair of French journalists, it's a breaking news story. To religious leaders, it's punishment for sins. As the sense of isolation and hopelessness grow, Dr Rieux and his associates begin to question their previously-accepted feelings of justice, loneliness, and love.

In the 1990s, a South American city is rocked by the imminent outbreak of a plague. While many attempt to flee the city, Dr Bernard Rieux sends his sick wife away and does his best to care for the plague's victims. The plague means different things to different people: to the doctor, it's a disease to be cured. To a pair of French journalists, it's a breaking news story. To religious leaders, it's punishment for sins. As the sense of isolation and hopelessness grow, Dr Rieux and his associates begin to question their previously-accepted feelings of justice, loneliness, and love.

張靖野再次以山林為背景，打造奇幻寓言《鼠疫》

西柏林，一家新落成的电影院正在派发电影票，招揽观众。影院首映的是一部名为《魔鬼》的恐怖影片。年轻女孩绮丽儿（Natasha Hovey 纳塔莎•霍维 饰）对影片颇感兴趣，她邀请好友凯茜（Paola Cozzo 饰）一同逃课前往电影院。 　　途中她们遇到另一伙年轻人，其中一个女人将影片宣传用的面具戴在脸上，却不慎割伤了皮肤。这个不慎的闪失导致了无可挽回的大灾难，该女子变成全身发绿的恐怖恶魔，凡是被她抓伤或咬到的也会产生同样的变化。人们四散逃命，恐怖迅速蔓延。绮丽儿她们该如何逃出生天呢？

1972年，纽约时报记者辛尼在柬埔寨采访，柬埔寨人潘迪是他的翻译兼助手，两人在战火纷飞中结下了深厚的友谊。1975年，红色高棉占领金边，辛尼进入法国领事馆后安全撤退，潘迪因为没有护照而被捕。潘迪在柬共的劳动改造政策中历经劫难，目睹了红色高棉政权的残暴血腥，1978年，越共入侵柬埔寨，潘迪趁机逃亡到泰国边境，与一直在寻找他的老朋友辛尼重逢。

一支电视台的摄制组正在调查拍摄一个传说中的恐怖禁地，在那里，他们发现一具恶魔的尸体。无意间，他们将恶魔复活，噩梦降临人间。 　　该纪录片通过电视播出，当一个女子正在观看时，突然片中的恶魔从电视机里爬出，随后展开血腥杀戮。被它攻击过的人不久也变成恐怖丧尸，四处寻找新的猎物。这个女子所在的大厦被某种怪异的力量封闭，正常的人类不断减少，丧尸数量则持续增加。是生是死？幸存者面临痛苦的抉择。为了活命，他们只有全力拚杀……